A Possible Consequence of Intravenously Infusing Antibodies into the Immune System

Posted on 2 CommentsPosted in Biology, Health, Health Sciences, Medicine, Neuroscience

Acute Tubular Necrosis (ATN) From Intravenous Immune Globulin (IVIG) Treatment for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Abstract: Infusions of IVIG are used to treat immune deficiency states, autoimmune disorders, and infections. IVIG Explanation and its relation to the Immune System: The immune system is a network of tissues and organs that work to defend the […]

Investigating the mouse brain for sex differences

Posted on Posted in Neuroscience, Other

Genes located only on the Y chromosome are male specific and are thus not expressed in female cells, which results in gene dependent sex differences. One of the genes located on the Y chromosome and expressed only in male cells is Kdm5d. In our study, the hypothalamus was compared between female and male SF-1 KO, intact WT and gonadectomised WT mice to investigate the genetically and hormonally dependent differences between the expression of the protein encoded by the Kdm5d gene. Standard immunohistochemical staining on floating brain sections was used to visualize the Kdm5d protein and was further analysed under the microscope. Immunoexpression of Kdm5d protein was observed only in WT intact males, but was not detected in any other groups. This observation suggests that the expression of the Kdm5d protein is both genetically and hormonally conditioned. Further experiments with testosterone supplementation should be carried out to confirm our findings. 

Remember that time?

Posted on Leave a commentPosted in Biology, Neuroscience

Since everyone in Years 11 and above will be, or at least should be, studying for exams around this time of year, it might be fun to think about the actual process of learning/memory itself. Before we start though,  it’s worth mentioning that with a topic like this it is far too easy to start considering […]